Proton Pump Inhibitors and Atrial Fibrillation

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  • Dustin Hughes
چکیده

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Case of paroxysmal atrial fibrillation improved after the administration of proton pump inhibitor for associated reflux esophagitis.

A 64-year-old man had demonstrated palpitations caused by paroxysmal atrial fibrillation (AF) documented by ambulatory electrocardiographic monitoring. Effectiveness of antiarrhythmic agent (disopyramide: 300 mg/day) was limited. Based on the gastrointestinal endoscopic findings, proton pump inhibitor (PPI: rabeprazole, 10 mg/day) was administered to eliminate heart burn due to reflux esophagit...

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Potential relationship between gastroesophageal reflux disease and atrial arrhythmias.

A potential reduction in symptoms related to atrial fibrillation after treatment of gastroesophageal reflux disease symptoms with proton pump inhibitor therapy has been previously described. However, illustration of this relationship by combined 24-hour pH and ambulatory Holter monitoring has not been performed. We report 3 patients with symptoms of both palpitations and reflux who underwent si...

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Effect of proton pump inhibitor use on Helicobacter pylori positivity and atrial fibrillation

License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be f...

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Co-prescribing of Warfarin with Statins and Proton Pump Inhibitors in Elderly Australians

Atrial Fibrillation (AF) is a common form of irregular heart rhythm increasing a person’s risk for ischaemic stroke by about fivefold [1]. The condition affects around 1.1% of Australians [2] and the prevalence increases with age, more than half of all atrial fibrillation patients are aged over 75 years [2]. Antithrombotic (anticoagulation or antiplatelet) therapy is recommended to reduce the r...

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Background Dabigatran is a direct thrombin inhibitor used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). Its prodrug, dabigatran etexilate (DE) is often co-administrated with a proton pump inhibitor (PPI) because of its adverse effects on the gastrointestinal tract. Drug-drug interactions between DE and PPIs in daily clinical practice have not ...

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تاریخ انتشار 2015